Non-Statin Therapies in Lipid Management: Practical Strategies for the Healthcare Team
Target Audience: Pharmacist, Pharmacy Tech, Physician Assistant, Physician
Course Overview
Despite the central role of statins in ASCVD risk reduction, many patients need additional or alternative therapies due to intolerance, suboptimal response, or residual risk. This continuing education activity will review the practical, evidence-based use of non-statin therapies and describe where each fits in contemporary clinical care pathways. Learners will review indications, dosing, safety and monitoring strategies, and cost and access issues. Throughout this activity, the focus will be on team-based strategies to optimize patient outcomes.
Learning Objectives
Upon completion of this educational activity, participants should be able to:
- Describe lipid physiology and non-statin therapy targets
- Identify indications, side effect profiles, and monitoring recommendations for lipid-lowering medications
- Identify pharmacologic options for patients when statin therapy is intolerable, contraindicated, or subtherapeutic
- Describe how healthcare team members can collaborate to develop patient-centered lipid management plans using non-statin therapies
Faculty
- Introduction
- Atherosclerotic Cardiovascular Disease
- Statins: Tolerability and Safety
- Lipid Physiology and Pathophysiology
- Patient Case
- Non-Statin Therapies
- Ezetimibe
- Evolocumab and Alirocumab
- Inclisiran
- Omega-3 Fatty Acids
- Bempedoic Acid
- Evinacumab
- Bile Acid Sequestrants
- Niacin
- Fibrates
- Return to Patient Case
- Nutraceutical Alternatives
- Summary
From January 12, 2026 through January 12, 2029, participants must:
- Read the "learning objectives" and "author and planning team disclosures"
- Study the section entitled "educational activity"
- Complete the Course Test and Evaluation form. The Course Test will be graded automatically. Following successful completion of the Course Test with a score of 70% or higher, a statement of participation will be made available immediately. (No partial credit will be given.)
Credit for this course will be automatically uploaded to CPE Monitor®.
Faculty Planner Disclosure
The following individuals were involved in developing this activity: L. Austin Fredrickson, MD, FACP, Liz Fredrickson, PharmD, BCPS, and Pamela Sardo, PharmD, BS. None of the individuals involved in developing this activity has a conflict of interest or financial relationships related to the subject matter. There are no financial relationships or commercial or financial support relevant to this activity to report or disclose by RxCe.com or any of the individuals involved in the development of this activity.
Unlabeled Use Disclosure
The information provided in this course is general in nature, and it is designed solely to provide participants with continuing education credit(s). This course and materials are not meant to substitute for the independent, professional judgment of any participant regarding that participant's professional practice, including but not limited to patient assessment, diagnosis, treatment, and/or health management. Medical and pharmacy practices, rules, and laws vary from state to state, and this course does not cover the laws of each state; therefore, participants must consult the laws of their state as they relate to their professional practice. Healthcare professionals must consult their employer, healthcare facility, hospital, or other organization for guidelines, protocols, and procedures to follow. The information provided in this course does not replace those guidelines, protocols, and procedures, but is for academic purposes only, and this course's limited purpose is for the completion of continuing education credits. Participants are advised and acknowledge that information related to medications, their administration, dosing, contraindications, adverse reactions, interactions, warnings, precautions, or accepted uses is constantly changing. Any person taking this course understands that such a person must make an independent review of medication information before any patient assessment, diagnosis, treatment and/or health management. Any discussion of off-label use of any medication, device, or procedure is informational only, and such uses are not endorsed hereby. Nothing contained in this course represents the opinions, views, judgments, or conclusions of RxCe.com LLC. RxCe.com LLC is not liable or responsible to any person for any inaccuracy, error, or omission with respect to this course or course material.
Please ensure the device you plan to use meets these requirements:
- Operating System: Windows 7, 8, 10, or 11 / Mac OS X 10.9 or later / iOS / Android
- Supported Browsers: Microsoft Edge, Firefox, Google Chrome, Safari, Opera
- A connection to the internet
Accreditation
In support of improving patient care, RxCE.com is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
PTCB Recognition
RxCe.com, LLC, offers pharmacy technician continuing education courses for PTCB recertification. Pharmacy technician courses are indicated both in the Target Audience description and the ACPE UAN which will end with a "T".