SUPPORTIVE CARE IN ONCOLOGY

Faculty:

L. Austin Fredrickson, MD, FACP 

L. Austin Fredrickson is an Associate Professor of Internal Medicine at Northeast Ohio Medical University, where he serves as core faculty and teaches diagnostics, therapeutics, clinical skills, and health humanities. He is board-certified in general internal medicine and practices rural primary care. 

Liz Fredrickson, PharmD, BCPS

Liz Fredrickson, PharmD, BCPS, is an Associate Professor of Pharmacy Practice and Pharmaceutical Sciences at the Northeast Ohio Medical University (NEOMED) College of Pharmacy, where she is course director of the Parenteral Products and Basic Pharmaceutics Lab courses.

Pamela Sardo, PharmD, BS

Pamela Sardo, PharmD, BS, is a freelance medical writer and licensed pharmacist. She is the founder and principal at Sardo Solutions in Texas. Pam received her BS from the University of Connecticut and her PharmD from the University of Rhode Island. Pam’s career spans many years in retail, clinics, hospitals, long-term care, Veterans Affairs, and managed health care responsibilities across a broad range of therapeutic classes and disease states.

Abstract

Supportive care is an essential component of comprehensive cancer treatment, aiming to improve the quality of life for patients and their families throughout their cancer journey. By implementing key strategies, healthcare providers can enhance patient comfort, reduce treatment-related complications, and support patients and their families as they navigate the complexities of cancer care. This activity will discuss the principles of supportive care, emphasizing its role in addressing the physical, emotional, and psychosocial needs of cancer patients. Supportive care models will be described, with a focus on the critical roles of members of the multidisciplinary care team, including physicians and pharmacy personnel. With a deeper understanding of supportive care, healthcare providers can enhance patient comfort, reduce treatment-related complications, and help patients and their families navigate the complexities of cancer care.

Accreditation Statements

In support of improving patient care, RxCe.com LLC is jointly accredited by the Accreditation CouncilTM for Continuing Medical Education (ACCME®), the Accreditation Council for Pharmacy Education (ACPE®), and the American Nurses Credentialing Center (ANCC®), to provide continuing education for the healthcare team.

Joint Universal Activity Number: The Joint Accreditation Universal Activity Numbers assigned to this activity are as follows:

Pharmacy Technicians: JA4008424-0000-26-111-H01-T

Credits: 2 contact hour(s) (0.2 CEU(s)) of continuing education credit.

Credit Types:

Pharmacy - 2 Credits

Type of Activity: Application

Media: Computer-Based Training (i.e., online courses)

Estimated time to complete activity: 2 contact hour(s) (0.2 CEU(s)), including Course Test and course evaluation

Release Date: June 25, 2026 Expiration Date: October 8, 2027

Target Audience: This educational activity is for Physicians, Physician Assistants, and Pharmacists.

How to Earn Credit: From June 25, 2026, through October 8, 2027, participants must:

Read the “learning objectives” and “author and planning team disclosures;”

Take the “Educational Activity Pre-Test;”

Study the section entitled “Educational Activity;” and

Complete the Educational Activity Post-Test and Activity Evaluation. The Educational Activity Post-Test will be graded automatically. Following successful completion of the Educational Activity Post-Test with a score of 70% or higher, a statement of participation will be made available immediately. (No partial credit will be given.)

CE and CME Credits: Credits for this course will be uploaded to CPE Monitor® for pharmacists and pharmacy technicians.

Statement of Need

Many oncology patients experience symptoms such as nausea, fatigue, pain, emotional distress, and nutritional problems. These symptoms interfere with treatment adherence, daily functioning, and recovery. Healthcare professionals are not uniformly aware of resources or the optimal way to address these concerns. It is important to recognize supportive care principles, understand multidisciplinary care models, and team roles. Applying evidence-based prevention and management strategies reduces symptom burden and can improve outcomes. As oncology treatment becomes more complex, this activity aims to provide resources for healthcare teams who need shared practical guidance to identify supportive care needs early and consistently.

Learning Objectives: Upon completion of this educational activity, participants should be able to:

Recognize the features of supportive care 

Describe supportive care models, including the roles of multidisciplinary care team members 

Describe supportive care, prevention, and management strategies

Disclosures

The following individuals were involved in planning, developing, and/or authoring this activity: L. Austin Fredrickson, MD, FACP; Liz Fredrickson, PharmD, BCPS; and Pamela Sardo, PharmD, BS. None of the individuals involved in developing this activity has any conflicts of interest or financial relationships related to the subject matter. There are no financial relationships or commercial or financial support relevant to this activity to report or disclose by RxCe.com or any of the individuals involved in the development of this activity.

© RxCe.com LLC 2026: All rights reserved. No reproduction of all or part of any content herein is allowed without the prior, written permission of RxCe.com LLC.

Educational Activity Pre-Test

Which feature of supportive care models involves patients receiving multiple supportive care services in a single setting to reduce wait times and redundancies?

Universal referral

Systematic screening

Collaborative teamwork

Streamlined care

Which of the following is true regarding pharmacotherapeutic treatments for cancer-related fatigue (CFR)?

Modafinil is not recommended for the control of CRF

Paroxetine is the gold standard for managing CRF

Long-term use of dexamethasone is appropriate for metastatic cancer patients with CRF

Nightly melatonin is recommended for managing CRF

The European Society for Medical Oncology (ESMO) guidelines recommend that healthcare professionals do which of the following for patients suffering from cancer-related fatigue?

Counsel patients that this is a short-term condition that will minimally impact their quality of life

Select a treatment primarily based on the patient’s age

Consider the patient’s severity of fatigue, preferences, and experiences to determine a treatment strategy

Prescribe an intensive exercise regimen

Educational Activity

Supportive Care in Oncology

Introduction

Supportive care is an essential component of comprehensive cancer treatment, aiming to improve the quality of life for patients and their families throughout their cancer journey. The benefits of supportive care include alleviating cancer symptoms and complications, preventing or reducing treatment-related toxicities, and generally improving a patient’s ability to tolerate treatments. As discussed in this course, these goals are advanced through improved communication between the patient and caregivers regarding the patient's disease. This course will also discuss how to address the emotional burden and provide psychosocial support for people with cancer.

Terminology and Principles of Supportive Care

The Multinational Association of Supportive Care in Cancer (MASCC) defines supportive care in cancer as the comprehensive prevention and management of physical and psychological side effects of cancer and its treatment.1 They state that this management addresses symptoms and side effects throughout the entire cancer journey, from diagnosis to post-treatment, to improve rehabilitation, secondary cancer prevention, survivorship, and end-of-life care.1 The primary goal of supportive care in cancer is to prevent and manage complications related to cancer and its treatment, ultimately improving the quality of life for patients and their caregivers.2 By minimizing the side effects of anticancer therapies, supportive care can also enhance treatment adherence, leading to improved outcomes such as prolonged survival or remission.2

The provision of supportive care involves the entire cancer care team, and all members of the multidisciplinary team must work in tandem to optimize patient care.2 This activity will discuss the principles of supportive care, emphasizing its role in addressing cancer patients' physical, emotional, and psychosocial needs. Various supportive care models will also be described, with a focus on the critical roles of members of the multidisciplinary care team, including physicians and pharmacy personnel. With a deeper understanding of supportive care, healthcare providers can enhance patient comfort, reduce treatment-related complications, and help patients and their families navigate the complexities of cancer care.

Definitions of supportive care vary among organizations and associations. The National Cancer Institute, or NCI, defines supportive care as “care given to improve the quality of life of people who have an illness or disease by preventing or treating, as early as possible, the symptoms of the disease and the side effects caused by treatment of the disease. Supportive care includes physical, psychological, social, and spiritual support for patients and their families. There are many components of supportive care, including pain management, nutritional support, counseling, exercise, music therapy, meditation, and palliative care. Supportive care may be provided alongside other treatments from diagnosis through the end of life.3 The MASCC defines supportive care as noted above and has identified numerous principles associated with supportive care (summarized in Table 1).4

Table 1

Principles of Supportive Care (MASCC)5

Supportive care aims to maintain (or improve) quality of life and to ensure that cancer patients can achieve maximum benefit from their anticancer treatment.
Supportive care is relevant throughout the continuum of the cancer experience, from diagnosis through treatment to post-treatment care (and encompasses cancer survivorship and palliative and end-of-life care).
Supportive care involves a coordinated, person-centric, and holistic (whole-person) approach, guided by the individual’s preferences and including appropriate support for their family and friends.
Supportive care (as outlined) is a basic right for all people with cancer, irrespective of their circumstances, their type of cancer, their stage of cancer, or their anticancer treatment. It should be available in all cancer centers and other medical facilities that routinely manage people with cancer.

Additional definitions pertinent to the provision of supportive care are defined in Table 2.2

Table 2

Supportive Care Terminology2

TerminologyDefinition
Supportive CareThe prevention and management of cancer's adverse effects, including physical and psychological symptoms, from diagnosis to post-treatment, aimed at improving rehabilitation, secondary prevention, survivorship, and end-of-life care.
Palliative CareHolistic care focuses on individuals with serious health-related suffering from severe illness, particularly those near the end of life, aiming to improve the quality of life for patients, families, and caregivers.
Early Palliative CarePalliative care is provided early in the course of life-threatening diseases, alongside active treatments like chemotherapy or radiotherapy in cases of advanced cancer.
Timely Palliative CarePersonalized palliative care is delivered at the optimal time and in the optimal setting, tailored to meet patients' specific needs.
Best Supportive CareNo standardized definition, though consensus guidelines exist for the best supportive care in clinical trials for advanced cancer.
Enhanced Supportive CareAn NHS England initiative to promote earlier integration of palliative care within cancer treatment, recognizing the benefits of specialist palliative care. Equivalent to early palliative care.
Supportive OncologyThose aspects of medical care are concerned with the physical, psychosocial, and spiritual issues faced by persons with cancer, their families, their communities, and their healthcare providers. In this context, supportive oncology refers to interventions to manage adverse effects of antineoplastic therapies and is now considered part of the broader rubric of palliative care.

In addition to creating these definitions, experts have developed consensus guidelines to provide standards for the term “best supportive care” used within clinical trials.2,5 These consensus guidelines are summarized in Table 3.5

Table 3

Consensus Guidelines for Best Supportive Care in Clinical Trials5

CategoryPatient Recommendations
Multidisciplinary Care- Access to palliative care specialists during anticancer therapy
- Access to nursing, social work, financial, and spiritual support
- Standard processes to educate patients on therapy goals, symptom assessment, and management in clinical trials
Documentation- Institutional review boards should ensure supportive care interventions are documented in trials with significant best supportive care components
- Supportive care delivery should be standardized for all patients in these trials
- Journal reports should clearly describe the best supportive care in relevant trials
Symptom Assessment- Symptoms assessed at baseline and regularly throughout the trial
- Use concise, globally accessible, validated tools for symptom assessment
- Symptom assessment intervals should be identical between the best supportive care and intervention groups
Symptom Management- Symptom control should follow evidence-based guidelines
- Clinical trial protocols should encourage guideline-based symptom control

Supportive Care Personnel and Models

The provision of supportive care often varies due to a lack of standard definitions, limited information regarding supportive care models, and a shortage of conceptual frameworks for supportive cancer care.6 Health care providers with a more complete understanding of these components could ultimately enhance the organization and effectiveness of supportive care services, thus improving patient outcomes.6 It is important to note that researchers have identified that supportive care needs to extend beyond just the provision of individualized service from providers, but aims to become a framework for planning and delivering optimized cancer care.7 Additionally, no matter which approach to care is taken, it is vital that the model can be adapted to be utilized for all patient populations.6

Optimizing supportive patient care should involve numerous healthcare specialties, including advanced practice providers, chaplains, dietitians, nurses, occupational and physical therapists, pharmacists, physicians, psychologists, and social workers.2,6 These disciplines should collaborate as an interdisciplinary team to provide specialized, comprehensive care tailored to the diverse needs of cancer patients. Individual providers should be well-versed in supportive care knowledge and concepts.6 The services teams provide are summarized in Table 4.6

Table 4

Supportive Care Services6

Supportive Care ServicesInterventions
Management of Cancer-Related Symptoms/Problems- Pain management
- Management of other symptoms
Management of Cancer Treatment-Related Symptoms- Prophylaxis (e.g., antiemetics for chemotherapy-induced nausea and vomiting)
- Treatment of side effects
Coordinating Management of Co-Morbidities- Collaboration with other specialties for comprehensive care
Psychological Support- Support for patients
- Support for carers (including children)
Nutritional Support- Guidance and interventions for nutritional health
Prehabilitation- Preparation for treatment to improve outcomes
Rehabilitation- Recovery support after treatment
Social Care- Advocacy
- Assistance with financial challenges ("financial toxicity")
Palliative Care- Early palliative care
- End-of-life care and bereavement support
Survivorship Care- Support for post-treatment health and wellness
Integrative Therapies- Complementary therapies to enhance quality of life

Care Team Timeout7

Supportive care teams should be available in outpatient and inpatient settings

These teams should closely cooperate with the patient’s primary care team and other relevant health and social care services

Barriers and challenges for care teams may include:

Lack of coordination

Poor communication between professionals and patients, and among professionals

Poor continuity of care

Non-standardized approaches to care

To address these issues, new roles have emerged: e.g., Patient navigators are professionals or volunteers who assist patients and families with decision-making, accessing services, and overcoming barriers

Service-driven care has been shown to demonstrate little value to patients and health systems

The unified supportive care model consolidates leadership and fosters collaborative teamwork to deliver streamlined care to cancer patients.2 This approach ensures that all cancer patients are universally referred for supportive care, where their unmet needs are systematically screened.2 This screening process helps guide appropriate interventions and facilitates the timely involvement of specialists tailored to each patient's specific needs.2 By promoting consistent messaging and coordinated efforts among team members, the unified care model enhances the overall care experience, ensuring that patients receive comprehensive, well-coordinated support throughout their treatment journey.2 Key features of supportive care models are summarized in Table 5.

Table 5

Features of Supportive Care6

FeatureDescription
Universal ReferralAll cancer patients are automatically referred from the time of diagnosis, as everyone can benefit from these services
Systematic ScreeningPatients are regularly screened for supportive care needs during consultations and visits, enabling tailored services and appropriate follow-up intensity.
Tailored Specialist InvolvementSpecialist care is provided by an interdisciplinary supportive/palliative care team, with timely involvement of other teams (e.g., cancer pain service, rehabilitation). Survivorship teams take over care for patients post-treatment.
Collaborative TeamworkThe integrated model fosters communication and collaboration among interdisciplinary team members, leveraging situational leadership for each discipline’s expertise.
Streamlined CarePatients receive multiple supportive care services in one setting, reducing wait times and duplication while ensuring consistent communication and care.
Consolidated LeadershipA unified administrative structure promotes institutional priorities in supportive care and fosters innovative interdisciplinary initiatives.
Improved OutcomesThis model improves access to patient-centered care, enhances outcomes, and reduces costs by eliminating service redundancies (e.g., overlapping care for pain and palliative services).

Care Team Timeout2,7

Digital health, telehealth, and eHealth refer to healthcare services supported by telecommunications or digital technology to enhance care.

Digital health interventions include:

Patient monitoring

Symptom management

Self-management

These interventions improve service efficiency and outcomes in supportive care

Collecting electronic patient-reported outcomes and using digital interventions (e.g., psychotherapeutic, mindfulness, exercise, and rehabilitation programs) improves cancer patients' distress, symptoms, and quality of life.

Remote monitoring enhances treatment adherence and efficacy and helps detect problems or relapses early.

Digital services should complement, not replace, in-person care.

Further research is needed to optimize the integration of digital interventions into routine practice.

Information sharing is a critical need in supportive care; a lack of clear, accessible, and culturally sensitive information can cause distress for patients and carers.

Involving patients and carers in service development helps meet their specific needs and preferences.

Prevention and Management Strategies

A key aspect of supportive care is managing a patient’s cancer and any treatment-related symptoms.6 Numerous chemotherapy agents have the potential to cause serious side effects if not appropriately managed.8 The adverse drug reactions (ADR) related to anticancer medications result from the medication’s mechanism of action; common side effects include things such as myelosuppression, diarrhea, mucositis, and infertility.8

This will require care teams to recognize signs and symptoms of chemotherapy-related complications and devise strategies for supportive care management.6 Two commonly encountered issues that will be discussed in further detail below include chemotherapy-induced nausea and vomiting (or CINV) and cancer-related fatigue.

Chemotherapy-Induced Nausea and Vomiting (CINV)

Nausea and vomiting are among the most prevalent and problematic side effects of chemotherapy. CINV is defined as nausea and vomiting due to the administration of chemotherapy, which impacts patients both psychologically and physically.8 The occurrence of CINV can be devastating for patients, with resulting complications such as weight loss, inability to provide self-care, and nutritional deficiencies.8

Guidelines for managing CINV have been published in concert by MASCC and the European Society for Medical Oncology (ESMO).9 These were last updated in 2023.9 The National Comprehensive Cancer Network also provides guidelines for treatment.8 Emetogenicity is defined as the probability of an agent causing nausea and vomiting, and this ultimately factors into the antiemetic prophylaxis strategy (prevention of nausea and vomiting) implemented.8 Authors of the guidelines have identified difficulties in accurately determining the emetic risk of chemotherapy agents due to variables such as tumor types, advanced vs. non-advanced disease, whether the patient is treatment-naïve, and whether agents are used singularly or in combination.9 Clinicians also need to take into consideration patient-specific factors such as age, gender, prior poor control of CINV, and conditions such as depression when selecting antiemetic prophylaxis.8 Anticancer therapies can be categorized into one of four groups based on emetogenic risk: highly emetogenic chemotherapy (CINV in >90% of patients), moderately emetogenic chemotherapy (CINV in 30-90% of patients), low emetogenic chemotherapy (CINV in 10-30% of patients), and minimally emetogenic (CINV in less than 10% of patients).8 Guidelines define the emetic risk of chemotherapy agents that are given intravenously as the risk of vomiting within 24 hours after starting therapy in patients who did not receive prophylaxis.9

The goal of prophylaxis is to prevent vomiting or nausea throughout the patient’s risk period.8 CINV prophylaxis regimens are detailed in Table 6.8

Table 6

CINV Prophylaxis Regimens8

CINV Prophylaxis Recommendations for IV Chemotherapy
RiskPhaseProphylaxis
HECAcute PhaseQuadruplet: 5-HT3-RA + dexamethasone + NK1-RA + olanzapine
Delayed Phase

Olanzapine on days 2-4

If used on day 1, oral aprepitant continues on days 2-3

If regimen other than AC, dexamethasone continues days 2-3 (dose varies by which NK1 receptor is utilized)

MECAcute PhaseDoublet: 5-HT3-RA + dexamethasone
Delayed PhaseDexamethasone 8 mg PO/IV on days 2-3 only if patients are receiving therapies with known potential for delayed CINV
LECAcute PhaseMonotherapy: 5-HT3-RA or dexamethasone
Delayed PhaseNone
MinimalAcute PhaseNone
DelayedNone

Role of the Primary Care Providers

Primary care providers help identify and manage symptoms of CINV.10,11 They should assess their patients for other causes of nausea and vomiting, such as dehydration, hypercalcemia, uremia, and infections.8 PCPs can also monitor for delayed-onset CINV, assess overall patient well-being, and provide early intervention by adjusting medications or referring patients back to oncology for specialized care.9,10 Also, they are instrumental in managing the broader health concerns of cancer patients, such as hydration status, electrolyte imbalances, and weight loss related to uncontrolled nausea and vomiting. 9,10 Congruent with supportive care models, these providers can ensure continuity of care by coordinating with oncologists and supportive care teams, ensuring optimal management of CINV in all treatment phases. 9,10

Role of the Pharmacist

Pharmacists play a critical role in preventing, recognizing, and managing CINV by ensuring the proper selection and administration of antiemetic therapy based on chemotherapy regimens, patient-specific factors, and established guidelines. They can also educate patients on the importance of adherence to prescribed antiemetics and potential side effects and assess patients for early signs of nausea and vomiting during routine consultations.8 By collaborating with the supportive care team, they may provide recommendations to modify antiemetic regimens when necessary and monitor for potential drug interactions between antiemetics and other medications the patient takes. Furthermore, pharmacists may recommend over-the-counter remedies and lifestyle modifications to manage mild symptoms.8

Role of the Pharmacy Technician

The oncology pharmacy technician plays a crucial role in supportive care for cancer patients by assisting pharmacists in preparing, dispensing, and managing chemotherapy and supportive care medications.12 Their responsibilities include ensuring accurate medication preparation, managing inventory of supportive care drugs, and helping with patient education by providing information on medication adherence and side effect management.12 They also collaborate with the oncology care team to ensure the timely and appropriate delivery of supportive care interventions, enhancing patient outcomes.12

Role of the Team

Clear referral criteria can be set in a care setting that prioritizes urgent same-day referrals for patients with physical or psychosocial distress.13 The clinic may be customized for patients with complex care needs, featuring low examination tables, a waiting room emphasizing privacy, ambient music, and standardized, comprehensive palliative care assessments.13 Some institutions embed a chaplain in an oncology clinic weekly, and social workers are included. An interdisciplinary intervention may be helpful to support patients with cancer who are at risk of opioid misuse.

A clinic can serve as a specialized setting for education and research. This model underscores the independent role of palliative care teams in cancer care. Criteria for outpatient palliative care referral may include physical or emotional symptoms, or a request for hastened death, spiritual crisis, or delirium.13

Cancer-Related Fatigue

From diagnosis through the end of treatment, fatigue has been identified as the most common symptom of patients with cancer.14 The ESMO guidelines define this fatigue as a distressing, persistent, subjective sense of physical, emotional, and/or cognitive tiredness or exhaustion related to cancer or cancer treatment that is not proportional to recent physical activity and that interferes with usual functioning.13 Cancer-related fatigue, or CRF, is particularly challenging as sleep or resting often does not relieve it.14 Cancer-related fatigue has been reported by up to 90% of patients with cancer undergoing treatment.14

The ESMO guidelines for CRF recommend implementing a shared decision-making model wherein the healthcare professional completes the following:14

Acknowledges the reality and impact of the condition and the symptoms

Provides information on the possible causes, nature, and course of CRF

Provides information about the range of interventions and management strategies available to the patient

Considers the person's age, the severity of their fatigue, their preferences and experiences, and the outcome of previous treatment(s) using a careful assessment regularly

Offers information about support groups for people with fatigue and their caregivers, if available

Patients with cancer should be screened for CRF, especially given that this can overlap with other common issues, including depression.13 Management can involve nonpharmacological modalities (including increased physical exercise and psychosocial interventions) and select medications. The ESMO guidelines have made the following recommendations in this area:14

The use of modafinil and armodafinil is not recommended for the control of CRF

Concerning the use of methylphenidate, dexmethylphenidate, long-acting methylphenidate, and dextroamphetamine, the panel has not reached a consensus:

For three panel members, the psychostimulants could be considered in thoroughly selected patients, and their usefulness and safety should be evaluated after a very short time period

For the other six panel members, psychostimulants cannot be recommended because most trials failed to show the intended effects on the primary outcome measures

The use of antidepressants, and in particular paroxetine, is not recommended for the control of CRF

The use of donepezil for the control of CRF is not recommended

Short-term use of dexamethasone or methylprednisolone is recommended for the control of CRF in metastatic cancer patients

The use of eszopiclone, megestrol acetate, and melatonin is not recommended for the control of CRF

Pharmacists can assist with the management of cancer-related fatigue by ensuring the appropriate selection and use of medications tailored to individual patient needs. Pharmacists should assess the use of medications that might contribute to fatigue (e.g., opioids, sedatives) and suggest alternatives or dosage adjustments. They may also recommend non-pharmacological interventions, such as physical activity and cognitive behavioral therapy (CBT), which have been shown to improve fatigue.

Additional Resources

MASCC (Multinational Association of Supportive Care in Cancer):

https://mascc.org/

The National Comprehensive Cancer Network (NCCN) website and patient support:

https://www.nccn.org/

https://www.nccn.org/patientresources/patient-resources

Association of Cancer Online Resources:

https://listserv.acor.org/scripts/wa-ACOR.exe?INDEX

Patient Case

A 68-year-old woman with metastatic breast cancer presents to the clinic for chemotherapy. She reports intermittent nausea, six-pound weight loss in one month, poor appetite, anxiety, and fatigue. Her vital signs are stable. She appears dehydrated.

Who are the possible team members to contact?

What are the possible next steps?

The oncology nurse, pharmacist, and physician discuss her symptoms, antiemetic regimen, hydration status, and need for support. The pharmacist screens for adherence, the nurse screens for symptom severity, and the impact on her function. The physician considers her regimen and treatment-related side effects. Recognizing the need for supportive services can help optimize a personalized approach to care, so the team discusses referrals to nutrition services and social work for appetite concerns, as well as coping strategies.

Summary

In oncology, supportive care is an essential component of comprehensive cancer treatment, aiming to improve the quality of life for patients and their families throughout their cancer journey. By implementing key strategies, healthcare providers can enhance patient comfort, reduce treatment-related complications, and support patients and their families as they navigate the complexities of cancer care.

References

MASCC. What is Supportive Care in Cancer? Accessed June 25, 2026. https://mascc.org/

Scotté F, Taylor A, Davies A. Supportive Care: The "Keystone" of Modern Oncology Practice. Cancers (Basel). 2023;15(15):3860. Published 2023 Jul 29. doi:10.3390/cancers15153860

National Cancer Institute NCI Dictionary of Cancer Terms: Supportive Care. Accessed June 25, 2026. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/supportive-care

Multinational Association of Supportive Care in Cancer Home Page. [(accessed on 10 May 2023)]. Available online: https://mascc.org [Ref list] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417474/

Zafar SY, Currow DC, Cherny N, Strasser F, Fowler R, Abernethy AP. Consensus-based standards for best supportive care in clinical trials in advanced cancer. Lancet Oncol. 2012;13(2):e77-e82. doi:10.1016/S1470-2045(11)70215-7

Hui D, Hoge G, Bruera E. Models of supportive care in oncology. Curr Opin Oncol. 2021;33(4):259-266. doi:10.1097/CCO.0000000000000733

Krishnasamy M, Hyatt A, Chung H, Gough K, Fitch M. Refocusing cancer supportive care: a framework for integrated cancer care. Support Care Cancer. 2022;31(1):14. Published 2022 Dec 14. doi:10.1007/s00520-022-07501-9

Clemmons AB, Glode AE. Supportive Care in Cancer. In: DiPiro JT, Yee GC, Haines ST, Nolin TD, Ellingrod VL, Posey L. eds. DiPiro’s Pharmacotherapy: A Pathophysiologic Approach, 12th Edition. McGraw Hill; 2023.

Herrstedt J, Celio L, Hesketh PJ, et al. 2023 updated MASCC/ESMO consensus recommendations: prevention of nausea and vomiting following high-emetic-risk antineoplastic agents. Support Care Cancer. 2023;32(1):47. Published 2023 Dec 21. doi:10.1007/s00520-023-08221-4

Hesketh PJ. Chemotherapy-induced nausea and vomiting. N Engl J Med. 2008;358(23):2482-2494.

Hui D, Hannon BL, Zimmermann C, Bruera E. Improving patient and caregiver outcomes in oncology: Team-based, timely, and targeted palliative care. CA Cancer J Clin. 2018;68(5):356-376. doi:10.3322/caac.21490

Lo A, Co M, Lo C, Chua D, Soltesz D. Specialized pharmacy oncology technician: experience at the ridge meadows hospital. Can J Hosp Pharm. 2010;63(2):138-141. doi:10.4212/cjhp.v63i2.899

Jordan K, et al. Antiemetics in cancer patients: ESMO clinical practice guidelines. Ann Oncol. 2020;31(10):1301-1305.

Fabi A, Bhargava R, Fatigoni S, et al. Cancer-related fatigue: ESMO Clinical Practice Guidelines for diagnosis and treatment. Ann Oncol. 2020;31(6):713-723. doi:10.1016/j.annonc.2020.02.016

DISCLAIMER

The information provided in this course is general in nature, and it is designed solely to provide participants with continuing education credit(s). This course and materials are not meant to substitute for the independent, professional judgment of any participant regarding that participant’s professional practice, including but not limited to patient assessment, diagnosis, treatment, and/or health management. Medical and pharmacy practices, rules, and laws vary from state to state, and this course does not cover the laws of each state; therefore, participants must consult the laws of their state as they relate to their professional practice.

Healthcare professionals must consult their employer, healthcare facility, hospital, or other organization for guidelines, protocols, and procedures to follow. The information provided in this course does not replace those guidelines, protocols, and procedures, but is for academic purposes only, and this course’s limited purpose is for the completion of continuing education credits.

Participants are advised and acknowledge that information related to medications, their administration, dosing, contraindications, adverse reactions, interactions, warnings, precautions, or accepted uses is constantly changing. Any person taking this course understands that such a person must make an independent review of medication information before any patient assessment, diagnosis, treatment and/or health management. Any discussion of off-label use of any medication, device, or procedure is informational only, and such uses are not endorsed hereby.

Nothing contained in this course represents the opinions, views, judgments, or conclusions of RxCe.com LLC. RxCe.com LLC is not liable or responsible to any person for any inaccuracy, error, or omission with respect to this course or course material.

© RxCe.com LLC 2026: All rights reserved. No reproduction of all or part of any content herein is allowed without the prior, written permission of RxCe.com LLC.

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