Prevention and Treatment of Osteoporosis
Monograph
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Course Summary
Osteoporosis is a common bone disease that affects over 10 million adults in the United States. Osteoporosis may lead to an increased risk of fractures due to weakening bone tissue, structure, and strength. Screening and evaluation are important to help diagnose osteoporosis. There is no cure for osteoporosis; however, several FDA-approved medications can help reduce fracture rates for patients with osteoporosis. Current FDA-approved pharmacologic options include bisphosphonates, estrogen-related therapy, parathyroid hormone analogs, RANK-ligand inhibitor, sclerostin inhibitor, and calcitonin salmon. Along with medications, several lifestyle modifications can help reduce fracture risks in patients with osteoporosis or low bone density.
Course Objectives
List the T-score values for patients with normal, low bone mass, and osteoporosis
Identify medication classes that may contribute to or worsen osteoporosis
Explain mechanisms of action for medications used to treat osteoporosis Describe lifestyle modifications to help decrease the risk of fractures
I. Introduction
II. Overview of Osteoporosis
III. Prevalence
IV. Bone Pathophysiology and Osteoporosis
V. Osteoporosis Screening Recommendations
VI. Diagnostic Criteria
1. Postmenopausal Women and Men Aged 50 and Older
2. Premenopausal Women and Men less than 50 Years of Age
VII. Risk Factors
1. Non-modifiable Risk Factors
2. Modifiable Risk Factors
VIII. Polypharmacy Concerns
IX. Fall and Fracture Reducing Lifestyle Modifications
X. Quality of Life Impacts
XI. Patient Education and General Treatment Considerations
XII. Nonpharmacologic Treatment for Osteoporosis
XIII. Pharmacologic Treatment Options
1. Preventative Vitamins and Minerals
2. Agents Inhibiting Bone Resorption
XIV. Treatment and Monitoring Considerations
XV. The Patient, Osteoporosis, and the Interdisciplinary Team
XVI. Summary
- Read the course objectives and faculty planner disclosure
- Read the course material
- Complete the post-test with a minimum score of 70% and complete the course evaluation form.
- Results are automatically submitted to CPE Monitor
Faculty Planner Disclosure
The following individuals were involved in developing this activity: Amanda Mayer, PharmD, Anna S. Smith, MPH, BSN-RN, Jeff Goldberg, PharmD, BCPP, and Pamela M. Sardo, PharmD, BS. Pamela Sardo, PharmD, BS, was an employee of Rhythm Pharmaceuticals until March 2022 and has no conflicts of interest or relationships regarding the subject matter discussed. There are no financial relationships relevant to this activity to report or disclose by any of the individuals involved in the development of this activity.
Unlabeled Use Disclosures
The information provided in this course is general in nature and it is solely designed to provide participants with continuing education credit(s). This course and materials are not meant to substitute for the independent, professional judgment of any participant regarding that participant’s professional practice, including but not limited to patient assessment, diagnosis, treatment and/or health management. Medical and pharmacy practices, rules, and laws vary from state to state, and this course does not cover the laws of each state; therefore, participants must consult the laws of their state as they relate to their professional practice. Healthcare professionals, including pharmacists and pharmacy technicians, must consult with their employer, healthcare facility, hospital, or other organization, for guidelines, protocols, and procedures they are to follow. The information provided in this course does not replace those guidelines, protocols, and procedures but is for academic purposes only, and this course’s limited purpose is for the completion of continuing education credits. Participants are advised and acknowledge that information related to medications, their administration, dosing, contraindications, adverse reactions, interactions, warnings, precautions, or accepted uses are constantly changing, and any person taking this course understands that such person must make an independent review of medication information prior to any patient assessment, diagnosis, treatment and/or health management. Any discussion of off-label use of any medication, device, or procedure is informational only and such uses are not endorsed hereby. Nothing contained in this course represents the opinions, views, judgments, or conclusions of RxCe.com LLC. RxCe.com LLC is not liable or responsible to any person for any inaccuracy, error, or omission with respect to this course, or course material.
Computer Hardware/Software Requirements
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- Target Audience: Pharmacist
- Contact Hours: 2.0 (0.2 CEUs)
- Activity Release Date: 5/16/2023
- Activity Expiration Date: 5/16/2026
- Activity Type: Knowledge
- UAN: 0669-0000-23-073-H01-P
- Topic: Disease State Management/Drug Therapy
- CeBroker Number: 20-1049220
Author:
RxCe.com, LLC is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.