Lipid Management: Beyond Statins

Pharmacist CEU
Contact Hours: 1.0 (0.1 CEUs)

Course Summary

Statins are a mainstay of lipid management and are generally safe and well-tolerated; however, in limited circumstances, they are not always the ideal choice for some patients. Non-statin medications may be necessary for certain circumstances, such as when patients cannot take or tolerate statins because they do not achieve the intended response from statins, or as additions to statin therapy. Pharmacists should be familiar with non-statin medications, including their indications, mechanisms of action, common and serious side effects, potential drug-drug interactions, and monitoring parameters. Pharmacists should also recognize that nutraceutical therapies exist, with variable evidence for use.

Course Objectives

Describe lipid physiology and non-statin therapy targets

Identify the indications, side effect profiles, and monitoring recommendations for lipid-lowering medications

Choose pharmacologic and nutraceutical options for patients when statins are intolerable, contraindicated, or subtherapeutic

I. Introduction

II. Atherosclerotic Cardiovascular Disease

1. Lipid Physiology
2. Dyslipidemia
3. Patient Evaluation
4. Statin Therapy

III. Non-Statin Therapies

1. Ezetimibe
2. Evolocumab and Alirocumab
3. Inclisiran
4. Omega-3 Fatty Acids
5. Bempedoic Acid
6. Evinacumab
7. Bile Acid Sequestrants
8. Niacin
9. Fibrates

IV. Economic Considerations

V. Nutraceutical Alternatives

VI. Summary

How to Earn Credit:
To earn credit for this course, participants must:
  1. Read the course objectives and faculty planner disclosure
  2. Read the course material
  3. Complete the post-test with a minimum score of 70% and complete the course evaluation form.
  4. Results are automatically submitted to CPE Monitor

Faculty Planner Disclosure

The following individuals were involved in the development of this activity: L. Austin Fredrickson, MD, FACP, Liz Fredrickson, PharmD, BCPS, and Susan DePasquale, MSN, PMHNP-BC. There are no financial relationships relevant to this activity to report or disclose by any of the individuals involved in the development of this activity.

Unlabeled Use Disclosures

The information provided in this course is general in nature and it is solely designed to provide participants with continuing education credit(s). This course and materials are not meant to substitute for the independent, professional judgment of any participant regarding that participant’s professional practice, including but not limited to patient assessment, diagnosis, treatment and/or health management. Medical and pharmacy practices, rules, and laws vary from state to state, and this course does not cover the laws of each state; therefore, participants must consult the laws of their state as they relate to their professional practice. Healthcare professionals, including pharmacists and pharmacy technicians, must consult with their employer, healthcare facility, hospital, or other organization, for guidelines, protocols, and procedures they are to follow. The information provided in this course does not replace those guidelines, protocols, and procedures but is for academic purposes only, and this course’s limited purpose is for the completion of continuing education credits. Participants are advised and acknowledge that information related to medications, their administration, dosing, contraindications, adverse reactions, interactions, warnings, precautions, or accepted uses are constantly changing, and any person taking this course understands that such person must make an independent review of medication information prior to any patient assessment, diagnosis, treatment and/or health management. Any discussion of off-label use of any medication, device, or procedure is informational only and such uses are not endorsed hereby. Nothing contained in this course represents the opinions, views, judgments, or conclusions of LLC. LLC is not liable or responsible to any person for any inaccuracy, error, or omission with respect to this course, or course material.

Computer Hardware/Software Requirements

Please ensure the device you plan to use meets these requirements and specifications:

  • Operating System: Windows 7,8,10, or 11 /Mac OS X 10.9 or later/iOS/Android
  • Supported Browsers: Microsoft Edge, Firefox, Google Chrome, Safari, Opera
  • A connection to the internet
  • For Live Webinars or Conferences: GoToWebinar application for iOS, Android, Mac, or PC. You cannot 'call into' a live conference.

  • Target Audience: Pharmacist
  • Contact Hours: 1.0 (0.1 CEUs)
  • Activity Release Date: 12/17/2022
  • Activity Expiration Date: 12/17/2025
  • Activity Type: Knowledge
  • UAN: 0669-0000-22-098-H01-P
  • Topic: Disease State Management/Drug Therapy
  • CeBroker Number: 20-998056


L. Austin Fredrickson, MD, FACP



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