
- Pharmacist
- 1.0
- 8/24/2022
- 8/24/2025
- Knowledge
- 0669-0000-22-003-H01-P
- Disease State Management/Drug Therapy
- 20-950068
- Identify the uses of gabapentin for the treatment of seizure disorders, pain management, and restless leg syndrome
- Describe the basic pharmacological profile, use, and clinical outcomes of gabapentin treatment
- Describe the potential contraindications and side effects
- Identify drug overdose and the use of drug tapering to discontinue gabapentin
I. Introduction
II. History of the Drug
III. Clinical Pharmacology
1. Mechanism of Action
2. Pharmacokinetics
3. Other Drugs Commonly Used to Treat Similar Pain
IV. Labeled and Off-label Uses for Gabapentin
1. Labeled Uses
2. Off-Label Uses
V. Administration and Dosage
1. Formulations and Strengths
2. Significant Warnings/Precautions
3. Adverse Reactions
4. Drug Interactions
5. Specific Populations
6. Lookalike/Soundalike Concerns
7. Storage and Handling
VI. Postmarketing Clinical Studies
1. Postherpetic Neuralgia
2. Restless Legs Syndrome
3. Diabetic Neuropathy
4. Fibromyalgia
5. Mood Disorders/Depression/Anxiety
6. Dystonias in Children
VII. Gabapentin Misuse
VIII. Gabapentin Overdose
1. Symptoms of Gabapentin Overdose
2. Risks Associated with Prescribing Gabapentin with Opioids
IX. Overdose Treatment
X. Withdrawal from Gabapentin
XI. Case Study: Gabapentin Withdrawal
XII. Summary