Dry Eye Disease and Perfluorohexyloctane as a Treatment Option

Pharmacist CEU
Contact Hours: 1.0 (0.1 CEUs)

Course Summary

More than 16 million people in the United States have dry eye disease. Effective treatments are needed to provide relief to these patients. In 2023, the Food and Drug Administration approved perfluorohexyloctane to treat dry eye disease. Perfluorohexyloctane is a semifluorinated alkane indicated for treating the signs and symptoms of dry eye disease (DED). Its exact mechanism of action is unknown but it forms a monolayer in the tear film to reduce evaporation. Clinicians may review the treatment options, the risk-benefit profiles of treatment options, and a patient’s medical history of dry eye disease. Following this analysis, the clinician and patient may consider whether perfluorohexyloctane can improve the patient’s outcomes.

Course Objectives

Define dry eye disease and its diverse clinical presentations

Describe the causes of dry eye disease

Compare the management of mild dry eye disease symptoms to the management of severe symptoms

Explain the resulting action of perflurohexyloctane

I. Introduction

II. Defining Dry Eye Disease

III. Epidemiology: Prevalence and Risk Factors for Dry Eyes

IV. Management of Symptoms of Dry Eyes

1. Mild Symptoms
2. Moderate to Severe Symptoms

V. Managing Symptoms of Dry Eyes Using Perfluorohexyloctane

1. Clinical Trials
2. Mechanism of Action
3. Indications
4. Dosing
5. Side Effects or Adverse Events
6. Drug-Drug Interactions
7. Handling and Storage

VI. Patient Counseling

VII. Interdisciplinary Approach and Collaboration

VIII. Summary

How to Earn Credit:
To earn credit for this course, participants must:
  1. Read the course objectives and faculty planner disclosure
  2. Read the course material
  3. Complete the post-test with a minimum score of 70% and complete the course evaluation form.
  4. Results are automatically submitted to CPE Monitor

Faculty Planner Disclosure

The following individuals were involved in developing this activity: Steven Malen, PharmD, MBA, and Pamela Sardo, PharmD, BS. Pamela Sardo, Pharm.D., B.S., was an employee of Rhythm Pharmaceuticals until March 2022 and has no conflicts of interest or relationships regarding the subject matter discussed. There are no financial relationships relevant to this activity to report or disclose by any of the individuals involved in the development of this activity.

Unlabeled Use Disclosures

The information provided in this course is general in nature and it is solely designed to provide participants with continuing education credit(s). This course and materials are not meant to substitute for the independent, professional judgment of any participant regarding that participant’s professional practice, including but not limited to patient assessment, diagnosis, treatment and/or health management. Medical and pharmacy practices, rules, and laws vary from state to state, and this course does not cover the laws of each state; therefore, participants must consult the laws of their state as they relate to their professional practice. Healthcare professionals, including pharmacists and pharmacy technicians, must consult with their employer, healthcare facility, hospital, or other organization, for guidelines, protocols, and procedures they are to follow. The information provided in this course does not replace those guidelines, protocols, and procedures but is for academic purposes only, and this course’s limited purpose is for the completion of continuing education credits. Participants are advised and acknowledge that information related to medications, their administration, dosing, contraindications, adverse reactions, interactions, warnings, precautions, or accepted uses are constantly changing, and any person taking this course understands that such person must make an independent review of medication information prior to any patient assessment, diagnosis, treatment and/or health management. Any discussion of off-label use of any medication, device, or procedure is informational only and such uses are not endorsed hereby. Nothing contained in this course represents the opinions, views, judgments, or conclusions of RxCe.com LLC. RxCe.com LLC is not liable or responsible to any person for any inaccuracy, error, or omission with respect to this course, or course material.

Computer Hardware/Software Requirements

Please ensure the device you plan to use meets these requirements and specifications:

  • Operating System: Windows 7,8,10, or 11 /Mac OS X 10.9 or later/iOS/Android
  • Supported Browsers: Microsoft Edge, Firefox, Google Chrome, Safari, Opera
  • A connection to the internet
  • For Live Webinars or Conferences: GoToWebinar application for iOS, Android, Mac, or PC. You cannot 'call into' a live conference.

  • Target Audience: Pharmacist
  • Contact Hours: 1.0 (0.1 CEUs)
  • Activity Release Date: 8/23/2023
  • Activity Expiration Date: 8/23/2026
  • Activity Type: Knowledge
  • UAN: 0669-0000-23-138-H01-P
  • Topic: Disease State Management/Drug Therapy
  • CeBroker Number: 20-1107208


Steve Malen, PharmD, MBA



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