
- Pharmacist
- 1.0
- 8/30/2022
- 8/30/2025
- Knowledge
- 0669-0000-22-020-H01-P
- Disease State Management/Drug Therapy
- 20-943098
- Describe the basic pharmacological profile, use, and clinical outcomes of asenapine treatment
- Identify the dosing and uses for asenapine
- Compare the benefits and risks of asenapine use for patients with chronic mental illness compared to other antipsychotics
- Identify the contraindications and potential side effects of asenapine
I. Introduction
II. Pharmacological Profile and Mechanism of Action
III. Dosing Recommendations for Asenapine
1. Bipolar I Disorder
2. Schizophrenia
3. Dosing Adjustments: Geriatrics, Renal and Hepatic Impairment
4. Drug-Drug Interactions
IV. Asenapine Treatment for Psychiatric Conditions
1. Bipolar I Disorder
2. Schizophrenia
V. Adverse Effects, Contraindications and Warnings
1. Elderly and Dementia
2. Temperature Regulation
3. Orthostatic Hypotension and Cardiovascular Conditions
4. Hematologic
5. Central Nervous System
6. Weight Gain, Hyperglycemia, and Dyslipidemia
7. Hyperprolactinemia
8. Gastrointestinal
9. Neuroleptic Malignant Syndrome (NMS)
10. Suicidal Behavior
11. Pregnancy and Breastfeeding
VI. Asenapine Case Studies
1. Case Study 1: Bipolar I Disorder with Mania
2. Case Study 2: Bipolar I Disorder
VII. Summary