Target Audience: Pharmacist, Pharmacy Technician 1.0 Credits Activity Release Date: 5/17/2021 12:00:00 AM Activity Expiration Date: 5/17/2024 12:00:00 AM Pharmacology
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Course Summary
Hyperprolactinemia is a well-known occurrence in people who are treated with psychotropic medications, notably antipsychotic medication for the treatment of schizophrenia and bipolar disorder. When reviewing the clinical effects of hyperprolactinemia with patients, pharmacists and prescribers should be discussing common clinical consequences and possible options of therapy. People who are diagnosed with a serious mental illness are at higher risk of developing hyperprolactinemia than healthy people within the general population. These patients require routine serum prolactin testing and physical assessment to determine whether complications of treatment have occurred. Hyperprolactinemia may cause clinically significant concerns that require consideration of treatment benefits and risks for a patient.
Course Objectives
  • Describe the methods of controlling elevated prolactin levels used to reduce the risk of hyperprolactinemia
  • Identify the well-known side effects of psychotropic medication, specifically from the use of antipsychotics in people with schizophrenia and bipolar disorder
  • Compare the risks and corresponding complications of hyperprolactinemia in males and females
  • Identify treatments that may lower serum prolactin levels
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Course Syllabus

I. Introduction

II. Prolactin: Secretion and Function

  1. Estrogen and Progesterone
  2. Other Factors Regulating Prolactin Secretion
  3. Function of Prolactin

III. Antipsychotic-induced Hyperprolactinemia

IV. Case Study: Hyperprolactinemia and Bromocriptine

V. Case Study: Aripiprazole and Levels of Hyperprolactinemia

VI. Summary

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